Global Longevity Federation

Wang Awarded $3.2M NIH Grant to Study Female Reproductive Aging

Understanding the precise mechanism by which the female organ ages is a prerequisite for ultimately developing counteracting measures for such a big problem. But in society, most of the attention has been focused on ovarian aging so farReadmore

Studying brain activity of swallowing helps researchers understand aging, disease

Researchers at the Beckman Institute for Advanced Science and Technology, Carle Hospital, and Purdue University teamed up to develop a new imaging tool that will improve our understanding of how the brain controls swallowing in both healthy patients and tReadmore

Study: Exercise slows aging process according to new mRNA measurements

Research conducted at Loma Linda University Health suggests that even small doses of regular exercise in sedentary older adults can have a significant effect in slowing the aging process at the level of molecular gene expression.Readmore

Roche Alzheimer’s disease Cerebrospinal Fluid (CSF) assays receive FDA clearance, supporting more accurate and timely diagnosis

Roche today announced that its Elecsys® beta-Amyloid (1-42) CSF II (Abeta42) and Elecsys® Phospho-Tau (181P) CSF (pTau181) assays have received U.S. Food and Drug Administration (FDA) 510(k) clearance. The Elecsys AD CSF Abeta42 and pTau181 assays (useReadmore

Research Snapshot: DNA replication discovery opens pathways to understanding and treating cancer, aging and degenerative disease

An international collaboration steered by David Cortez, Richard N. Armstrong, Ph.D. Chair for Innovation in Biochemistry, explored how cells tolerate DNA damage and genome instability—and they arrived at conclusions that will redirect research into DNA Readmore

Decade-long research project that explores aging in South Africa receives NIH/NIA funding for additional waves and national expansion, with a special emphasis on cognitive health

Researchers from the Harvard Center for Population and Development Studies (HCPDS), the Harvard T.H. Chan School of Public Health, the University of the Witwatersrand, and the University of Cape Town have been awarded $27 million from the National InstituReadmore

Taurine May Be a Key to Longer and Healthier Life

Anew study led by Columbia researchers involving dozens of aging researchers around the world found that taurine supplements can slow down the aging process in worms, mice, and monkeys and can even extend the healthy lifespans of middle-aged mice by up Readmore

Longevity gene from naked mole rats extends lifespan of mice

In a groundbreaking endeavor, researchers at the University of Rochester have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse’s lifespan.Readmore

AI algorithms find drugs that could combat ageing

Three drugs that could help stave off the effects of ageing have been discovered using artificial intelligence (AI), a study by Edinburgh researchers suggests.Readmore

Stanford Medicine researchers build an eye ‘aging clock’ that could lead to treatments for ocular diseases

Stanford Medicine researchers clock the age of cells to find new therapy targetsReadmore

Restoring nerve-muscle connections boosts strength of aging mice, Stanford Medicine study finds

A drug that boosts strength in injured or aging mice restores connections between nerves and muscle and suggests ways to combat weakness in humans due to aging, injury or diseaseReadmore

Cell protein discovery points to healthier ageing

Researchers at The University of Queensland have found an anti-ageing function in a protein deep within human cellsReadmore

Researcher uses AI to understand how healthy older adults are aging at home

University of Toronto nursing researcher Charlene Chu wants to know how older adults age at home – and she’s using artificial intelligence to help. Readmore

Running Throughout Middle Age Keeps ‘Old’ Adult-Born Neurons ‘Wired’

For the study, researchers focused on the effects of long-term running on a network of new hippocampal neurons that were generated in young adult mice, at middle age. These “mice on the run” demonstrate that running throughout middle age keeps old aduReadmore

Multivitamin Improves Memory in Older Adults, Study Finds

By the end of the first year, memory improved for people taking a daily multivitamin, compared with those taking a placebo. The researchers estimate the improvement, which was sustained over the three-year study period, was equivalent to about three yearsReadmore

Decrease Oxygen to Boost Longevity? Study in mice suggests that oxygen restriction could extend life span

• Living in a low-oxygen environment extended life spans, preserved neurologic function in mice. • Findings add to a growing body of research showing oxygen restriction may ward off neurologic decline and extend life span in animal models. • MechaReadmore

Age is just a number: How older adults view healthy aging

A new McKinsey Health Institute (MHI) survey of more than 21,000 older adults (defined as those aged 55 and older) across 21 countries finds that respondents largely agree about the importance of having purpose, managing stress, enjoying meaningful connecReadmore

Tracking our aging brains

Researchers work across disciplines to explore line between natural aging, cognitive diseaseReadmore

Scientists Slow Aging by Engineering Longevity in Cells

In this study, the researchers genetically rewired the circuit that controls cell aging. From its normal role functioning like a toggle switch, they engineered a negative feedback loop to stall the aging process. The rewired circuit operates as a clock-liReadmore

Accelerated Biological Aging May Contribute to Depression and Anxiety

A study by researchers at Columbia Mailman School of Public Health and Peking University School of Public Health provides some of the first, large-scale evidence that processes of biological aging may contribute to the risk of depression and anxiety.Readmore

Retinal scans: A non-invasive, inexpensive method to track human aging

The blood vessel-rich tissue in the retina, can be used to track human aging, in a way that is non-invasive, less expensive and more accurate than other aging clocks that are currently available.Readmore

FUNDING BY THE MARGA AND WALTER BOLL FOUNDATION

Peter Tessarz investigates the ageing of the liverReadmore

Scientists identify a method to rejuvenate old stem cells

A research team led by Dr. Thomas Rando, director of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, has discovered that restoring glutathione—a key antioxidant that prevents cell damage—rejuvenates old muscle Readmore

Digital Markers Near-Perfect for Predicting Dementia

Researchers develop highly accurate machine learning model for early detection of mild cognitive impairment and dementia in older driversReadmore

SEX-SPECIFIC DIFFERENCES IN RESPONSE TO REDUCED INSULIN ACTIVITY

Neurons (green) in the male brain react differently to lowered insulin signaling. Readmore

Scientists identify drug that could extend lifespan

New Zealand researchers identify drug with potential for longer and healthier ageing. Readmore

How Brain Regions Involved in Wakeful Rest May Play a Role in the Risk for Alzheimer’s Disease

By identifying patterns in the brains of healthy, aging people, scientists may not only have a future target for intervention but have a larger window of time in which to treat before symptoms are seen.Readmore

HOW OLD IS YOUR BRAIN, REALLY? ARTIFICIAL INTELLIGENCE KNOWS

AI-powered analysis developed at USC accurately reflects risk of cognitive decline and Alzheimer’s disease based on brain age.Readmore

The Buck Institute Launches First Human Clinical Trial Effort marks the first study of ketone body supplementation in healthy older adults; participants will be recruited in Marin County

The Buck Institute for Research on Aging has launched its first human clinical trial. The BIKE (Buck Institute Ketone Ester) pilot study is the first trial in the world to look at the effects of ketone ester supplementation in the context of agingReadmore

MITOCHONDRIA PRODUCE ANTIOXIDANTS TO PROTECT OUR CELLS FROM DYING

The enzyme STARD7 (green) helps mitochondria (red) to transport Coenzyme Q to protect cells from cell death. Readmore

Lessons on Human Longevity … From Rockfish

Multi-species analyses reveal shared genes linked to longer life spanReadmore

CAB Member Elected APHA President-Elect

Flint Community Advisory Board member Ms. Ella Greene-Moton, has been elected President-Elect of the American Public Health Association!Readmore

Cellular rejuvenation therapy safely reverses signs of aging in mice

Salk researchers treated mice with anti-aging regimen beginning in middle age and found no increase in cancer or other health problems later onReadmore

FEBS EXCELLENCE AWARD FOR STEPHANIE PANIER

Stephanie Panier investigates how cells detect and repair DNA damage. Award supports highly competitive research in molecular life sciences Readmore

DO WOMEN AGE DIFFERENTLY FROM MEN?

Studies in fruit flies reveal how the sex determines the responses to the anti-ageing drug rapamycinReadmore

NEW DFG RESEARCH GROUP INVESTIGATES CAUSES AND CONSEQUENCES OF GENOME INSTABILITY

By understanding the basic mechanisms of genome stability, the scientists hope to develop new therapeutic approaches for the chronic diseases that are rising sharply in our ageing society, ranging from dementia to chronic kidney diseases and cardiovasculaReadmore

Brain aging is not one-size-fit-all: Chronological age, biological age and gender affect the shrinkage of different brain areas.

The results of the study, appearing in The Proceedings of the National Academy of Sciences, show that functional brain networks are affected in different ways by aging, gender and blood immune factors.Readmore

Immunis Chairman Dr. Hans Keirstead Delivered Keynote at the Aging and Gerontology Conference in Dubai

The Aging and Gerontology conference is focused on cellular & molecular repair of age-associated disease.Readmore

New study expands range of potential Alzheimer's drugs

Alzheimer's disease is associated with a reduction of insulin receptors in brain microvessels, Readmore

Landmark Study of Biomarker Data May Enable Better Treatment for Early Onset Dementia

Biomarker Changes May Help with Prediction of Symptoms in Familial Frontotemporal DementiaReadmore

Lecanemab Confirmatory Phase 3 Clarity AD Study Met Primary Endpoint

Lecanemab Confirmatory Phase 3 Clarity AD Study Met Primary Endpoint, Showing Highly Statistically Significant Reduction of Clinical Decline in Large Global Clinical Study of 1,795 Participants with Early Alzheimer’s DiseaseReadmore

NUHS opens Singapore’s first Centre for Healthy Longevity to increase healthy lifespan of Singapore population by five more disease-free years

A world's first integrated pre-clinical and clinical ageing research institute that is poised to lead the Longevity Medicine field with clinical research to prolong healthspan by delay ageing.Readmore

Changes to outdated Medicaid limits could improve eligibility for vulnerable seniors

A new analysis published today in the Health Affairs, University of Pittsburgh Health scientists propose...Readmore

Damaged telomeres in the elderly may increase susceptibility to SARS-CoV-2

SARS-CoV-2 causes the pandemic coronavirus disease COVID-19, that is more harmful for elderly people, who show more....Readmore

Improving mobility and quality of life for older adults

As we get older, transportation provides a vital link between home and community Without reliable and easy ways to get around...Readmore

Effects of digital technologies on older people's access to health and social care

The 2020 COVID-19 pandemic prompted the rapid implementation of new and existing digital technologies to facilitate access...Readmore

Dental device for snoring may slow onset of Alzheimer's disease

A good night's sleep plays an essential role in regulating brain health by removing the waste material and toxins...Readmore

Loss of Epigenetic Information Can Drive Aging, Restoration Can Reverse It

The ICE method offers researchers a new way to explore the role of epigenetics in aging and other biological processes.Readmore

High Risk/High Reward Grant Funds Development of Smart Drug Delivery System to Treat Multiple Alzheimer’s Pathologies

The Buck’s $2.4 million Transformative Research Award is one of just nine in the nation.Readmore

FDA Grants Accelerated Approval for Alzheimer’s Disease Treatment

Today, the U.S. Food and Drug Administration approved Leqembi (lecanemab-irmb) via the Accelerated Approval pathway for the treatment of Alzheimer’s disease. Readmore

SENS Research Foundation & Underdog Pharmaceuticals jointly awarded $252,000 NIA research grant

The National Institute on Aging (NIA) division of the National Institutes of Health (NIH) has awarded a grant to advance research on Engineered Cyclodextrins targeting toxic oxidized cholesterol to eradicate atherosclerosis...Readmore

FAU AWARDED $1 MILLION GRANT TO HELP PREVENT INJURY, DEATH FROM FALLS

Every second, an older person in the U.S. falls and injures themselves, and every 20 minutes one of them dies from the fall.Readmore

21 start-ups selected to innovate for healthy ageing

EIT Health, together with eight global collaborators representing nearly 50 countries and territories, today announced the winners of the inaugural round of Healthy Longevity Catalyst Awards.Readmore